Xamarin has gradually shifted its focus from independent developers to enterprise development teams, and it will now be able to leverage Microsoft's existing enterprise relationships and sales processes. Similarly, Microsoft now can approach enterprises with a complete native cross-platform development model, rather than its previous mix of Universal Windows Platform and Apache Cordova hybrid applications. Through the free Visual Studio Community edition, Microsoft will be able to deliver Xamarin's development tooling to a wider selection of student, open source, and independent developers than the current MSDN subscription that included Xamarin was able to reach. Integrating Xamarin subscriptions into the new Visual Studio subscriptions shouldn't be hard, as both have comparable tiers.
Adding cross-platform tools to its development platform makes a lot of sense for Microsoft, opening up the Android and iOS worlds to .Net and helping deliver the endpoints that Satya Nadella's cloud-first, mobile-first world needs. The acquisition should close before Microsoft's 2016 Build developer event at the end of March.
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